TABLE 2

Characteristics of flbA suppressors

DominanceaSuppression
Allele37°25°STb (30°)flbA98 Δ flbA Δ fluGfadAd+c
sfaA1 SRR +
sfaC67 DRD++
sfaD82 DRD++
sfaE83 DSD+++
fadA R205H DRD++
fadA G203R DDD+++/–
Δ fadA RRR++
  • a Domimance was determined using homozygous flbA diploids. R, recessive; D,domninant; S, semidominant.

  • b Sterigmatocystin production at 30°

  • c sfaE83 was able to suppress all three dominant activating fadA mutations: G42R, R178C, and Q204L.