TABLE 2

Sensitivity of the estimation method to AT(GC)- skewness and among-site rate variation assessed by simulations

Human-like ancestoraMouse-like ancestorb
AT- and GC-skewnessc2.50.52.50.5
080.0/1080.7/10 78.8/1063.9/1067.3/965.7/10
0.280.2/1081.7/1080.9/1066.0/969.5/1069.0/8
0.479.1/1078.9/1080.0/1064.0/969.8/668.8/7
0.676.7/873.9/779.3/973.0/572.8/472.7/3
0.876.4/877.2/878.9/1072.3/674.6/373.9/2
  • a True ancestral G + C-content, 80%.

  • b True ancestral G + C-content, 65%.

  • c Shape parameters of the assumed gamma distribution among sites. Infinite means constant rates. Values given are mean estimated ancestral G + C-content (%)/number of successes (out of 10).