TABLE 4

Intrinsic thermotolerance of daf-2 hermaphrodites

StrainaMedian survival (hr)% N2bMaximum survival (hr)% N2Nc
N27.1 ± 0.58.6 ± 0.9514 (7)
Class 1
e13658.6 ± 0.3123 ± 611.0 ± 1.0130 ± 12299 (4)
m5778.0 ± 0.8104 ± 910.0 ± 2.0110 ± 10151 (2)
sa1938.11171012569 (1)
e13719.3 ± 0.4134 ± 613.0 ± 1.7155 ± 29275 (2)
e136810.0 ± 1.1144 ± 1813.0 ± 1.7154 ± 22305 (4)
m417.9 ± 0.2109 ± 910.5 ± 0.9118 ± 10256 (5)
m21211.6 ± 0.7166 ± 1215.0 ± 1.0188 ± 13166 (2)
e136912.4 ± 1.0178 ± 1715.0 ± 1.0188 ± 13136 (2)
Class 2
m12010.31661215057 (1)
e137012.2 ± 0.7172 ± 1516.4 ± 0.8197 ± 21363 (5)
m59611.2 ± 0.9163 ± 1214.5 ± 15.0172 ± 28153 (2)
m57912.1 ± 0.1178 ± 114.0 ± 1.0156 ± 11117 (2)
e139111.8 ± 0.8168 ± 915.0 ± 1.0188 ± 13163 (2)
e97912.3 ± 0.1175 ± 316.0 ± 0.0200 ± 0163 (2)
sa223NDNDNDNDND
  • ND, not determined.

  • a Alleles ranked in order of increasing severity of L2d and dauer arrest phenotype, within each class.

  • b To calculate these values, mutant median survival at 35° was expressed as a percentage of the wild-type control in each respective trial, and then the mean and standard error were calculated from the set of percentages. For this reason, these values cannot be derived directly from the values in the preceding columns.

  • c Total number of animals; in parentheses, number of trials.