TABLE 3

Adult life span

15°22.5°
AlleleaMedianMaximumNbMedianMaximumNc
+24.0 ± 1.631.0 ± 3.0304 (5)16.3 ± 1.322.2 ± 2.4306 (6)
daf-12(m20)16.7 ± 0.624.8 ± 4.180 (4)10.6 ± 1.416.0 ± 1.280 (4)
Class 1
daf-2(e1365)28.2 ± 2.936.5 ± 2.5224 (2)29.2 ± 3.039.7 ± 8.3257 (3)
daf-2(m577)25.8 ± 1.134.0 ± 4.3269 (4)25.9 ± 3.840.3 ± 6.6246 (4)
daf-2(sa193)33.5 ± 1.240.5 ± 1.541 (2)26.0 ± 2.035.0 ± 1.039 (2)
daf-2(e1371)31.8 ± 2.845.5 ± 2.2273 (4)21.6 ± 0.536.3 ± 5.6247 (4)
daf-2(e1368)33.2 ± 3.247.5 ± 5.3263 (4)29.5 ± 4.243.3 ± 8.6223 (4)
daf-2(m41)27.0 ± 1.335.0 ± 1.471 (3)29.4 ± 1.235.0 ± 0.060 (2)
daf-2(m212)48.4 ± 1.464.0 ± 0.040 (2)34.0 ± 3.047.5 ± 4.538 (2)
daf-2(e1369)52.8 ± 2.874.5 ± 1.5213 (2)38.2 ± 2.454.8 ± 3.1232 (4)
daf-2(e1365); daf-12(m20)18.2 ± 1.529.7 ± 3.864 (3)15.2 ± 2.324.0 ± 4.777 (4)
daf-2(m577); daf-12(m20)21.6 ± 3.232.7 ± 1.961 (3)18.5 ± 7.533.8 ± 1.189 (4)
daf-2(sa193); daf-12(m20)26.7 ± 2.442.0 ± 9.041 (2)18.4 ± 2.629.5 ± 3.091 (4)
daf-2(m41); daf-12(m20)24.6 ± 3.932.8 ± 6.089 (4)17.9 ± 4.841.3 ± 4.788 (4)
daf-2(m212); daf-12(m20)25.3 ± 5.651.1 ± 7.078 (4)34.0 ± 7.052.5 ± 3.680 (4)
Class 2
daf-2(m120)32.3 ± 1.850.0 ± 3.0252 (2)31.6 ± 4.457.8 ± 7.2257 (4)
daf-2(e1370)33.8 ± 0.242.0 ± 1.466 (3)20.4 ± 2.445.0 ± 0.039 (2)
daf-2(m596)36.8 ± 5.356.5 ± 4.5208 (2)35.4 ± 3.854.3 ± 4.6257 (3)
daf-2(m579)44.3 ± 1.363.5 ± 1.5239 (2)40.0 ± 3.264.3 ± 15.0266 (3)
daf-2(e1391)63.4 ± 5.091.3 ± 10.9259 (3)29.2 ± 9.768.0 ± 10.0142 (3)
daf-2(e979)50.3 ± 2.869.0 ± 3.0105 (4)28.3 ± 1.756 ± 12.057 (2)
daf-2(sa223)58.7 ± 2.792.0 ± 2.036 (2)41.0 ± 2.053.0 ± 3.037 (2)
daf-2(e1370); daf-12(m20)30.4 ± 2.041.7 ± 2.165 (3)21.6 ± 4.662.5 ± 1.788 (4)
daf-2(e1391); daf-12(m20)58.7 ± 8.081.3 ± 9.669 (3)71.8 ± 2.294.0 ± 7.094 (4)
daf-2(e979); daf-12(m20)45.6 ± 4.891.5 ± 13.537 (2)43.3 ± 8.772.0 ± 2.986 (4)
  • a daf-2 alleles ordered in increasing severity of L2d and dauer arrest phenotype, within each class.

  • b Sample size; number of trials in parentheses.