TABLE 2

Percentage larval arrest by daf-2 mutants

15°20°22.5°25.5°
AlleleaDaf-cbNDaf-cbNDaf-cbNDaf-cbN
N202521027430313301710
Class 1
el365c027780.1 ± 0.129290264196 ± 2d1725
m577c01988028510259096 ± 2d1945
sa193NDfNDf030030 (11 ± 2)g267585 ± 7e1580
e1371022880.1 ± 0.325920 (58 ± 11)g281097 ± 0.9e2070
e1368015160.3 ± 0.326411.5 ± 0.9295389 ± 2e1543
m410252314 ± 4209675 ± 9229697 ± 2d1508
m21228 ± 9237399.5 ± 0.4315999.6 ± 0.5e173897 ± 5e1530
e136955 ± 61637100 ± 0.32489100250099 ± 0.6d1965
Class 2
m120029660238710 ± 4296999 ± 0.6e1229
e1370019050.5 ± 0.7264114 ± 5 (21 ± 8)h231897 ± 2d1543
m596017990.4 ± 0.4192652 ± 11213895 ± 2d1532
m579018390215550 ± 10(70 ± 10)h220596 ± 4e1140
e13915±3179166 ± 7211899 ± 0.7d135390 ± 3e873
e97920 ± 3213498 ± 0.8d235799 ± 1d18470i605
s32230j290k1303.3 ± 4l10295 ± 10l31
  • a Ranked in approximate order of increasing severity with respect to L2d and dauer arrest, within each class.

  • b Values ± standard error, calculated from the percentage dauer larva formation among progeny (complete broods) of 10 individual animals.

  • c Ranking of e1365 above m577 based upon suppression of e1365 Age phenotype by daf-12(m20). See Table 3.

  • d All animals not arrested at the dauer stage arrested as unhatched eggs, Lis, or early L2s.

  • e All animals not arrested at the dauer stage arrested as unhatched eggs, L1s or early L2s, or developed into adults.

  • f Not determined.

  • g Transient dauer larvae; scored at 48 hr.

  • h Arrest at L2d or dauer stage.

  • i 24% embryonic arrest, 76% L1 arrest.

  • j 48% embryonic arrest, 14% L1 or L2 arrest, 38% L2d arrest.

  • k 92% L2d arrest, 1% L1 arrest, 7% embryonic arrest.

  • l All animals that did not arrest at the dauer stage arrested development as L2ds.