TABLE 1

Prior phenotypic analysis of daf-2 alleles

AlleleFeatures describedSource
e979aEmbryonic and L1 arrest, Daf-c1
e1368Daf-c, epistasis, temperature-sensitive period2, 3
e1370Isolation, Daf-c, epistasis, life span, brood size1, 2, 4–9
e1391Daf-c, epistasis, life span, brood size2, 9
m41Daf-c, epistasis, life span, brood size7
m65Daf-c, epistasis7
sa193Isolation, Daf-c, life span5, 10
sa223Isolation, Daf-c, adult sterility10
  • References: 1, Vowels and Thomas (1992); 2, Riddle et al. (1981); 3, Swanson and Riddle (1981); 4, Riddle (1977); 5, Kenyon et al. (1993); 6, Gottlieb and Ruvkun (1994); 7, Larsen et al. (1995); 8, Dorman et al. (1995); 9, Tissenbaum and Ruvkun (1998); and 10, Malone and Thomas (1994), which describes the Daf-c phenotype of a further seven daf-2 alleles.

  • a daf-2(e979) (reference strain CB 1286) is referred to as daf-2(e1286) in reference 1.