TABLE 3

Summary of mutant phenotypes

MutationCytological phenotypeEmb phenotypeaLarval arrestbSterile phenotype(% penetrance)Unc phenotype (severity)Vulval defectsc
stu-8(oj1)Moderate (mm)+100StrongP, V
abc-1(oj2)Nuclear division defectiveStrong (mm)+++100StrongP, V
spd-1(oj5)Spindle defective/cytokinesis defectiveStrong (mm)+>100StrongP
zyg-1(oj7)Centrosome duplication defectiveStrong (mm)++100StrongV, P, M
stu-9(oj13)Moderate (mm)+100Weak
stu-10(oj14)Abnormal spindle alignmentModerate (mm)+100WeakP
stu-11(oj18)Abnormal spindle alignmentModerate (mm)>100Weak
stu-12(oj21)Moderate (mm)+>100WeakP
slo-1(oj23)Slow developmentStrong (mn)+>100Weak
stu-13(oj24)Strong (mn)+>100Weak
stu-14(oj26)Moderate++>100WeakP
(mm)
stu-15(oj28)Strong (mn)+100StrongP, M, V
spd-2(oj29)Abnormal microtubule organizationStrong (mm)+++100StrongV, P
stu-16(oj30)Moderate (mn)+>100StrongP, V
stu-17(oj31)Moderate (mm)>100WeakV
stu-18(oj32)Abnormal centrosome morphologyModerate (mn)+++>100WeakM
stu-19(oj33)Strong (mm)+100Weak
cyk-2(oj34)Cytokinesis defectiveModerate (mn)+100Weak
spd-3(oj35)Abnormal microtubule organizationStrong (mm)+>100WeakV
  • a Letters in parentheses indicate genes in which maternal gene expression is required for viability (mm) and genes in which maternal or zygotic expression is sufficient for viability (mn).

  • b Penetrance of larval arrest indicated as follows: +, 0-10%; + +, 10-20%; + + +, >20%.

  • c Vulval defects are listed in order of highest penetrance. P, Pvl; V, Vul; M, Muv.