TABLE 1

Coding sequence divergence among D. melanogaster, D. simulans and D. yakuba

SynonymousReplacement
GeneLengthEstimate of number of substitutions per siteLengthEstimate of number of substitutions per site
Adha
mel-sim199.40.0559 ± 0.0174565.60.0043 ± 0.0028
mel-yak0.1577 ± 0.03130.0115 ± 0.0045
sim-yak0.1338 ± 0.02810.0107 ± 0.0044
pera
mel-sim410.80.1216 ± 0.01881268.20.0020 ± 0.0012
mel-yak0.3112 ± 0.03320.0242 ± 0.0044
sim-yak0.2654 ± 0.02950.0242 ± 0.0044
Amy-proximal
mel-sim356.60.0928 ± 0.01701122.50.0099 ± 0.0030
mel-yak0.1224 ± 0.02000.0180 ± 0.0040
sim-yak0.0862 ± 0.01630.0099 ± 0.0030
sry
mel-sim412.10.1229 ± 0.01891043.90.0116 ± 0.0034
mel-yak0.2728 ± 0.03130.0283 ± 0.0053
sim-yak0.1905 ± 0.02460.0204 ± 0.0045
nullo
mel-sim136.80.0941 ± 0.0279384.20.0212 ± 0.0075
mel-yak0.5274 ± 0.08780.0568 ± 0.0125
sim-yak0.4684 ± 0.07900.0624 ± 0.0132
G6pd
mel-sim377.70.1113 ± 0.01821177.30.0189 ± 0.0040
mel-yak0.1485 ± 0.02210.0163 ± 0.0038
sim-yak0.1536 ± 0.02220.0268 ± 0.0048
bossa
mel-sim416.30.0902 ± 0.01561149.70.0042 ± 0.0019
mel-yak0.1874 ± 0.02430.0053 ± 0.0021
sim-yak0.1670 ± 0.02250.0018 ± 0.0012
Rh3a
mel-sim307.00.0833 ± 0.0174839.00.0036 ± 0.0021
mel-yak0.1644 ± 0.02560.0036 ± 0.0021
sim-yak0.1527 ± 0.02470.0
ac
mel-sim168.20.0971 ± 0.0261431.80.0093 ± 0.0047
mel-yak0.1622 ± 0.03510.0429 ± 0.0102
sim-yak0.1949 ± 0.03990.0356 ± 0.0092
sc
mel-sim253.40.0929 ± 0.0203742.60.0150 ± 0.0045
mel-yak0.2396 ± 0.03630.0233 ± 0.0057
sim-yak0.2009 ± 0.03220.0191 ± 0.0051
l'sc
mel-sim198.40.0364 ± 0.0140566.60.0107 ± 0.0044
mel-yak0.2738 ± 0.04600.0197 ± 0.0060
sim-yak0.2669 ± 0.04540.0161 ± 0.0054
asea
mel-sim290.70.0506 ± 0.0139771.40.0168 ± 0.0047
mel-yak0.2484 ± 0.03530.0339 ± 0.0068
sim-yak0.2390 ± 0.03420.0244 ± 0.0057
cia
mel-sim246.20.1011 ± 0.0218711.80.0303 ± 0.0066
mel-yak0.2214 ± 0.03540.0464 ± 0.0083
sim-yak0.2497 ± 0.03820.0406 ± 0.0077
  • The numbers of synonymous and replacement sites were calculated by Ina's (1995) method. The number of substitutions per site was estimated by Kimura's (1980) formulae.

  • a The numbers of differences are the means for multiple alleles described in materials and methods.