TABLE 2

Mutation rates in exonuclease mutants

Mutation ratea × 109
StrainDescriptionRifrNalrLeu+
BT199Exo+101.50.38
STL2694ExoI101.50.52
STL2347ExoVII8.44.30.09
STL2331RecJ4.61.60.56
STL2758ExoI ExoVII3.40.40.17
STL2729ExoI Rec J4.41.00.75
STL2348ExoVII RecJ6.00.30.07
STL2700ExoI ExoVII RecJ170.20.34
STL1526UvrD120322.1
STL773MutS2203305.1
  • a Mutation rates were determined as described in materials and methods. Reported rates for each strain represent averages among at least two sets of eight independent cultures for Rif and Nal and one set for Leu.