TABLE 4

Mutation rates per genome per replication in microbes with DNA chromosomes

OrganismGμbμg
Bacteriophage M136.4 × 1037.2 × 10−70.0046
Bacteriophage λ4.9 × 1047.7 × 10−80.0038
Bacteriophages T2 and T41.7 × 1052.4 × 10−80.0040
Escherichia coli4.6 × 1065.4 × 10−100.0025
Saccharomyces cerevisiae1.2 × 1072.2 × 10−100.0027
Neurospora crassa4.2 × 1077.2 × 10−110.0030
Mean0.0034
  • Values are from Drake (1991), excluding the two well defined outliers and updated slightly as described in the text. The updated G values are 168.8 kb for phage T4 (Kutter et al. 1994), 4639 kb for E. coli (Blattner et al. 1997) and 12068 kb for S. cerevisiae (Goffeau et al. 1996).