TABLE 1
Parameters used in describing the mutation process
| Parameter | Definition |
|---|---|
| Abbreviations | |
| b | Base or base pair |
| kb | Kilobase or kilobase pair |
| Parameters | |
| C | The variously calculated ratio of total mutations to observed mutations |
| f | Mutant fraction in a population |
| G | Genome size in bases or base pairs (haploid unless otherwise indicated) |
| Ge | Effective genome size (portion in which most mutations are deleterious) |
| h | Dominance coefficient associated with a typical detrimental mutation |
| ΔM | Rate of decline per generation of the mean of a quantitative fitness trait |
| N | Population size |
 | Mean reduction in trait value of a single mutation when homozygous |
 | Mean selection coefficient against a heterozygous deleterious mutation |
| U | Rate of deleterious mutations per genome per sexual generation |
| Uc | U for a chromosome |
| Ud | U for the diploid genome |
| Uh | U for the haploid genome |
| ΔV | Increase in variance of a quantitative fitness trait in parallel lines |
| δ | Reduction in mean fitness of inbred versus randomly mated diploids |
| μb | Mutation rate per base pair per replication |
| μg | Mutation rate per genome per replication |
| μeg | Mutation rate per effective genome per replication |
| μegs | Mutation rate per effective genome per sexual generation |
| μlin | Mutation rate under conditions of linear replication in RNA viruses |
| μbin | Mutation rate under conditions of binary replication in RNA viruses |
| μm | (μlin + μbin)/2 for RNA viruses |