Parameters used in describing the mutation process
Parameter | Definition |
---|---|
Abbreviations | |
b | Base or base pair |
kb | Kilobase or kilobase pair |
Parameters | |
C | The variously calculated ratio of total mutations to observed mutations |
f | Mutant fraction in a population |
G | Genome size in bases or base pairs (haploid unless otherwise indicated) |
Ge | Effective genome size (portion in which most mutations are deleterious) |
h | Dominance coefficient associated with a typical detrimental mutation |
ΔM | Rate of decline per generation of the mean of a quantitative fitness trait |
N | Population size |
![]() | Mean reduction in trait value of a single mutation when homozygous |
![]() | Mean selection coefficient against a heterozygous deleterious mutation |
U | Rate of deleterious mutations per genome per sexual generation |
Uc | U for a chromosome |
Ud | U for the diploid genome |
Uh | U for the haploid genome |
ΔV | Increase in variance of a quantitative fitness trait in parallel lines |
δ | Reduction in mean fitness of inbred versus randomly mated diploids |
μb | Mutation rate per base pair per replication |
μg | Mutation rate per genome per replication |
μeg | Mutation rate per effective genome per replication |
μegs | Mutation rate per effective genome per sexual generation |
μlin | Mutation rate under conditions of linear replication in RNA viruses |
μbin | Mutation rate under conditions of binary replication in RNA viruses |
μm | (μlin + μbin)/2 for RNA viruses |