TABLE 3

Demonstration of repeatability of the spontaneous reversion rate assay: Results of repeated compartmentalization tests for base substitutions in his1-7 (his1-798) of strain XV185-14C

Experiment numberCells/compartment (×10−6)Number of compartmentsNumber of compartments with mutantsBackground mutants/compartment (×108)Mutation rate (×108)
CNN − N0mbMa
8809211914981050.0326.16
8810162284971260.0306.34
890401-12994821460.0316.01
890401-22455001370.0316.51
890401-32805001480.0206.24
89050528047914106.23
8905142314881340.0216.92
  • a M = reversions/cell/generation.