Repair efficiencies of loops and single-base mismatches in wild-type and mutant cells

Percent segregation (n)b
StrainsaCross 1B Loop onlyCross 2B Loop + SBMMCross 3 SBMM only
K1c + MTCHO+6 (47)15 (26)0 (12)
Clone B10 (39)35 (29)53 (40)
  • a K1c and MTCHO+ are mismatch repair proficient; clone B is mismatch repair deficient.

  • b Percentage of products that had one or more segregating markers; n, number of products tested; SBMM, single-base mismatches.