TABLE 3

age-1 (hx546) has reduced maternal and zygotic age-1 activity

Paternal genotypeMaternal genotypeZygotic genotypeAge phenotypeLife span relative to wild type
Dauer formationLife span (days)
+/++/+nondauer (n > 1000)8.9 ± 0.2 (n = 170)1.0
mg44/mnC1mg44/mg44nondauer (n = 505)a20.7 ± 0.2 (n = 26)2.2
mg44/mnC1mg44/mnC1nondauer (n > 1000)10.4 ± 0.8 (n = 22)1.2
mg44/mg44mg44/mg44dauer (n = 505)
hx546/hx546hx546/hx546nondauer (n > 1000)15.6 ± 0.7 (n = 108)1.8
hx546/hx546bhx546/hx546bnondauer (n > 100)14.8 ± 0.9 (n = 40)1.7
+/+mg44/mg44mg44/+nondauer (n > 100)10.7 ± 0.5 (n = 35)1.2
+/+hx546/hx546hx546/+nondauer (n > 50)12.0 ± 1.2 (n = 20)1.4
hx546/hx546mg44/mg44hx546/mg44nondauer (n > 100)19.8 ± 1.1 (n = 54)2.2
mg44/hx546mg44/mg44dauer (n = 406)
mg44/hx546mg44/hx546nondauer (n > 1000)19.3 ± 0.9 (n = 32)2.2
mg44/hx546hx546/hx546nondauer (n > 300)19.1 ± 1.2 (n = 21)2.2
hx546/hx546mg44/mnC1hx546/mg44nondauer (n > 100)15.8 ± 1.4 (n = 30)1.8
hx546/hx546mg44/mnC1hx546/mnC1nondauer (n > 100)10.7 ± 0.6 (n = 23)1.2
+/+mg44/mnC1mg44/+nondauer (n > 100)9.7 ± 0.6 (n = 31)1.0
+/+mg44/mnC1+/mnC1nondauer (n > 100)10.0 ± 0.9 (n = 21)1.1
  • Some of the data presented here has been previously published in Morris et al. (1996).

  • a 1% of the animals formed dauer larvae and 20% formed sterile adults.

  • b age-1(hx546) backcrossed strain that is marked with sqt-1(sc13).

  • All values are mean ± SE.