TABLE 2

Summary of ND2 variation in humans and chimpanzees

ND2
Sηηeπ ± SD (per site)θ ± SD (per site)
Humans (n = 21)
All sites2021150.0024 ± 0.00150.0053 ± 0.0021
Nonsynonymous101070.0017 ± 0.00120.0035 ± 0.0016
Synonymous101180.0046 ± 0.00340.0109 ± 0.0049
All chimpanzees (n = 21)
All sites4852210.0102 ± 0.00540.0128 ± 0.0046
Nonsynonymous121240.0031 ± 0.00200.0042 ± 0.0018
Synonymous3640170.0312 ± 0.01690.0394 ± 0.0145
P. t. verus (n = 19a)
All sites2839170.0073 ± 0.00400.0077 ± 0.0030
Nonsynonymous6740.0018 ± 0.00130.0022 ± 0.0011
Synonymous2232130.0235 ± 0.01310.0248 ± 0.0098
  • S, number of polymorphic sites; η, total number of mutations; ηe, number of unambiguous mutations in the external branches (inferred from Figure 2); π, average number of pairwise nucleotide differences per site between sequences; θ, average number of nucleotides segregating per site. SD, standard deviation. Values of π and θ and their standard deviations were calculated as outlined in materials and methods. No multiple-hit correction was made. The total number of sites compared for the ND2 gene was 1041. The numbers of nonsynonymous (787) and synonymous (254) sites were estimated using the method of Li (1993).

  • a Excluding individuals Pt175 and Pt176 because they are not from the P. t. verus subspecies.