Table 1

Genes and mutations identified in the dopamine resistance screen

GeneAllelesProteinHuman ortholog
goa-1nd64G-protein α-subunitο
dgk-1nd48, nd55Diacylglycerol kinaseDGKθ
egl-30nd50G-protein α-subunitq
dop-3nd41D2-like receptorD2 receptor
glr-1nd38AMPA-type glutamate-gated cation channel subunitGluRd2
ace-1nd35Class A acetylcholinesteraseAcetylcholinesterase