RT Journal Article
SR Electronic
T1 A Novel Cell Death Gene Acts to Repair Patterning Defects in <em>Drosophila melanogaster</em>
JF Genetics
JO Genetics
FD Genetics Society of America
SP 739
OP 742
DO 10.1534/genetics.114.163337
VO 197
IS 2
A1 Tanaka, Kentaro M.
A1 Takahashi, Aya
A1 Fuse, Naoyuki
A1 Takano-Shimizu-Kouno, Toshiyuki
YR 2014
UL http://www.genetics.org/content/197/2/739.abstract
AB Cell death is a mechanism utilized by organisms to eliminate excess cells during development. Here, we describe a novel regulator of caspase-independent cell death, Mabiki (Mabi), that is involved in the repair of the head patterning defects caused by extra copies of bicoid in Drosophila melanogaster. Mabiki functions together with caspase-dependent cell death mechanisms to provide robustness during development.