RT Journal Article
SR Electronic
T1 Suppressors, Screens, and Genes: An Educational Primer for Use with “A Network of Genes Antagonistic to the LIN-35 Retinoblastoma Protein of <em>Caenorhabditis elegans</em>”
JF Genetics
JO Genetics
FD Genetics Society of America
SP 1031
OP 1035
DO 10.1534/genetics.112.142943
VO 191
IS 4
A1 De Stasio, Elizabeth A.
YR 2012
UL http://www.genetics.org/content/191/4/1031.abstract
AB An article by Polley and Fay in this issue of GENETICS provides an excellent opportunity to introduce or reinforce concepts of reverse genetics and RNA interference, suppressor screens, synthetic phenotypes, and phenocopy. Necessary background, explanations of these concepts, and a sample approach to classroom use of the original article, including discussion questions, are provided.