RT Journal Article
SR Electronic
T1 NUMERICAL ANALYSIS OF WEAK RANDOM DRIFT IN A CLINE
JF Genetics
JO Genetics
FD Genetics Society of America
SP 297
OP 303
VO 92
IS 1
A1 Luskin, Mitchell
A1 Nagylaki, Thomas
YR 1979
UL http://www.genetics.org/content/92/1/297.abstract
AB The equilibrium state of a diffusion model for weak random genetic drift in a cline is analyzed numerically. The monoecious organism occupies an unbounded linear habitat with constant, uniform population density. Migration is homogeneous, symmetric, and independent of genotype. A single diallelic locus with a step environment is investigated in the absence of dominance and mutation. The ratio of the variance of either gene frequency to the product of the expected gene frequencies decreases monotonically to a non-zero constant. The correlation between the gene frequencies at two points decreases monotonically to zero as the separation is increased with the average position fixed; the decrease is asymptotically exponential. The correlation decreases monotonically to a positive constant depending 011 the separation as the average position increasingly deviates from the center of the cline with the separation fixed. The correlation also decreases monotonically to zero if one of the points is fixed and the other is moved outward in the habitat, the ultimate decrease again being exponential. All the results are parameter free. Some asymptotic formulae are derived analytically.