RT Journal Article
SR Electronic
T1 Adaptation of a Quantitative Trait to a Moving Optimum
JF Genetics
JO Genetics
FD Genetics Society of America
SP 715
OP 719
DO 10.1534/genetics.106.067215
VO 176
IS 1
A1 Kopp, Michael
A1 Hermisson, Joachim
YR 2007
UL http://www.genetics.org/content/176/1/715.abstract
AB We investigate adaptive evolution of a quantitative trait under stabilizing selection with a moving optimum. We characterize three regimes, depending on whether (1) the beneficial mutation rate, (2) the fixation time, or (3) the rate of environmental change is the limiting factor for adaptation. If the environment is rate limiting, mutations with a small phenotypic effect are prefered over large mutations, in contrast to standard theory.