%0 Journal Article
%A Zhao, Hongyu
%A Speed, Terence P.
%T Statistical Analysis of Half-Tetrads
%D 1998
%J Genetics
%P 473-485
%V 150
%N 1
%X Half-tetrads, where two meiotic products from a single meiosis are recovered together, arise in different forms in a variety of organisms. Closely related to ordered tetrads, half-tetrads yield information on chromatid interference, chiasma interference, and centromere positions. In this article, for different half-tetrad types and different marker configurations, we derive the relations between multilocus half-tetrad probabilities and multilocus ordered tetrad probabilities. These relations are used to obtain equality and inequality constraints among multilocus half-tetrad probabilities that are imposed by the assumption of no chromatid interference. We illustrate how to apply these results to study chiasma interference and to map centromeres using multilocus half-tetrad data.
%U https://www.genetics.org/content/genetics/150/1/473.full.pdf