PT - JOURNAL ARTICLE
AU - Fu, Yun-Xin
TI - Coalescent Theory for a Partially Selfing Population
DP - 1997 Aug 01
TA - Genetics
PG - 1489--1499
VI - 146
IP - 4
4099 - http://www.genetics.org/content/146/4/1489.short
4100 - http://www.genetics.org/content/146/4/1489.full
SO - Genetics1997 Aug 01; 146
AB - A coalescent theory for a sample of DNA sequences from a partially selfing diploid population and an algorithm for simulating such samples are developed in this article. Approximate formulas are given for the expectation and the variance of the number of segregating sites in a sample of k sequences from n individuals. Several new estimators of the important parameters θ = 4Nμ and the selfing rate s, where N and μ are, respectively, the effective population size and the mutation rate per sequence per generation, are proposed and their sampling properties are studied.