TY - JOUR
T1 - Coalescent Theory for a Partially Selfing Population
JF - Genetics
JO - Genetics
SP - 1489
LP - 1499
VL - 146
IS - 4
AU - Fu, Yun-Xin
Y1 - 1997/08/01
UR - http://www.genetics.org/content/146/4/1489.abstract
N2 - A coalescent theory for a sample of DNA sequences from a partially selfing diploid population and an algorithm for simulating such samples are developed in this article. Approximate formulas are given for the expectation and the variance of the number of segregating sites in a sample of k sequences from n individuals. Several new estimators of the important parameters θ = 4Nμ and the selfing rate s, where N and μ are, respectively, the effective population size and the mutation rate per sequence per generation, are proposed and their sampling properties are studied.
ER -