RT Journal Article
SR Electronic
T1 A genetic map of the mouse suitable for typing intraspecific crosses.
JF Genetics
JO Genetics
FD Genetics Society of America
SP 423
OP 447
VO 131
IS 2
A1 Dietrich, W
A1 Katz, H
A1 Lincoln, S E
A1 Shin, H S
A1 Friedman, J
A1 Dracopoli, N C
A1 Lander, E S
YR 1992
UL http://www.genetics.org/content/131/2/423.abstract
AB We report the construction of a genetic linkage map of the mouse, consisting entirely of genetic markers that can be rapidly typed by polymerase chain reaction and that show a high degree of polymorphism among inbred laboratory strains. Specifically, the map contains 317 simple sequence length polymorphisms at an average spacing of 4.3 cM and is detectably linked to approximately 99% of the mouse genome. In typical crosses between inbred laboratory strains, about 50% of the markers are polymorphic, making it straightforward to follow inheritance in almost any cross.