Identifying Causal Variants at Loci with Multiple Signals of Association

Farhad Hormozdiari; Emrah Kostem; Eun Yong Kang; Bogdan Pasaniuc; Eleazar Eskin

doi:10.1534/genetics.114.167908

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Identifying Causal Variants at Loci with Multiple Signals of Association

Farhad Hormozdiari, Emrah Kostem, Eun Yong Kang, Bogdan Pasaniuc and Eleazar Eskin

Genetics October 1, 2014 vol. 198 no. 2 497-508; https://doi.org/10.1534/genetics.114.167908

Farhad Hormozdiari

*Department of Computer Science, University of California, Los Angeles, California 90095

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Emrah Kostem

*Department of Computer Science, University of California, Los Angeles, California 90095

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Eun Yong Kang

*Department of Computer Science, University of California, Los Angeles, California 90095

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Bogdan Pasaniuc

†Department of Human Genetics, University of California, Los Angeles, California 90095

‡Department of Pathology and Laboratory Medicine, University of California, Los Angeles, California 90095

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Eleazar Eskin

*Department of Computer Science, University of California, Los Angeles, California 90095

†Department of Human Genetics, University of California, Los Angeles, California 90095

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For correspondence: eeskin@cs.ucla.edu

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- Supporting Information: File S1, Tables S1-S3, and Figure S1 (PDF, 129 KB)
- File S1: Materials and Methods (PDF, 122 KB)
- Table S1: Relation between the p*, configuration size and recall rate in regions with low amounts of LD. (PDF, 71 KB)
- Table S2: Relation between the p*, configuration size and recall rate in regions with high amounts of LD. (PDF, 71 KB)
- Table S3: Comparison between the solution obtained from solving the posterior probability exactly or using the greedy method. (PDF, 71 KB)
- Figure S1: The patterns between the number of individuals collected in each study and the number of causal SNPs selected by CAVIAR. (PDF, 31 KB)

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Volume 198 Issue 2, October 2014

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Identifying Causal Variants at Loci with Multiple Signals of Association

Farhad Hormozdiari, Emrah Kostem, Eun Yong Kang, Bogdan Pasaniuc and Eleazar Eskin

Genetics October 1, 2014 vol. 198 no. 2 497-508; https://doi.org/10.1534/genetics.114.167908

Farhad Hormozdiari

*Department of Computer Science, University of California, Los Angeles, California 90095

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Emrah Kostem

*Department of Computer Science, University of California, Los Angeles, California 90095

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Eun Yong Kang

*Department of Computer Science, University of California, Los Angeles, California 90095

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Bogdan Pasaniuc

†Department of Human Genetics, University of California, Los Angeles, California 90095

‡Department of Pathology and Laboratory Medicine, University of California, Los Angeles, California 90095

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Eleazar Eskin

*Department of Computer Science, University of California, Los Angeles, California 90095

†Department of Human Genetics, University of California, Los Angeles, California 90095

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For correspondence: eeskin@cs.ucla.edu

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Identifying Causal Variants at Loci with Multiple Signals of Association

Farhad Hormozdiari, Emrah Kostem, Eun Yong Kang, Bogdan Pasaniuc and Eleazar Eskin

Genetics October 1, 2014 vol. 198 no. 2 497-508; https://doi.org/10.1534/genetics.114.167908

Farhad Hormozdiari

*Department of Computer Science, University of California, Los Angeles, California 90095

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Search for this author on this site

Emrah Kostem

*Department of Computer Science, University of California, Los Angeles, California 90095

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Eun Yong Kang

*Department of Computer Science, University of California, Los Angeles, California 90095

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Bogdan Pasaniuc

†Department of Human Genetics, University of California, Los Angeles, California 90095

‡Department of Pathology and Laboratory Medicine, University of California, Los Angeles, California 90095

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Eleazar Eskin

*Department of Computer Science, University of California, Los Angeles, California 90095

†Department of Human Genetics, University of California, Los Angeles, California 90095

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Search for this author on this site
For correspondence: eeskin@cs.ucla.edu

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