Files in this data supplement:

• Supporting Information: File S1, Figures S1-S5, Tables S1-S6, and Supporting Information Literature Cited (PDF, 540 KB)
• File S1: Supplementary Materials and Methods (PDF, 159 KB)
• Figure S1: Survival of cdc-25.1 RNAi-treated skpo-1 animal lines on E. faecalis. (PDF, 175 KB)
• Figure S2: Lifespan defect of skpo-1 mutants on E. coli OP50 without prior cdc-25.1 exposure. (PDF, 167 KB)
• Figure S3: skpo-1 mutants display a lifespan defect on heat-killed E. coli OP50. (PDF, 169 KB)
• Figure S4: The skpo-1 mutant does not have increased intestinal bacterial load during E. faecalis infection. (PDF, 221 KB)
• Figure S5: clec-60 expression is elevated in skpo-1 mutant animals, relative to wild type, in response to E. faecalis infection. (PDF, 204 KB)
• Table S1: Median survival and P-values of E. faecalis OG1RF killing assays. (PDF, 145 KB)
• Table S2: Median survival and P-values of E. coli OP50 longevity assays. (PDF, 144 KB)
• Table S3: Data for Relative Mortality Calculation (PDF, 113 KB)
• Table S4: Median survival and P-values of P. aeruginosa PA14 killing assays. (PDF, 144 KB)
• Table S5: Primers for cDNA inserts ligated into pL4440 construct for dsRNA production in E. coli. (PDF, 144 KB)
• Table S6: qRT-PCR primers for assessing expression of innate immune response genes in response to E. faecalis. (PDF, 165 KB)