Specialization of Function Among Aldehyde Dehydrogenases: The ALD2 and ALD3 Genes Are Required for β-Alanine Biosynthesis in Saccharomyces cerevisiae

W. Hunter White; Paul L. Skatrud; Zhixiong Xue; Jeremy H. Toyn

Article Information

vol. 163 no. 1 69-77

PubMed

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History

Received June 20, 2002
Accepted October 21, 2002
Published online January 1, 2003.

Author Information

W. Hunter White*,
Paul L. Skatrud*,
Zhixiong Xue‡ and
Jeremy H. Toyn†,1

^* Elanco Animal Health, a Division of Eli Lilly and Company, Greenfield, Indiana 46140
^‡ DuPont Central Research, Wilmington, Delaware 19880
^† Department of Chemical Enzymology, Bristol-Myers Squibb, Wilmington, Delaware 19880

↵1 Corresponding author: Department of Chemical Enzymology, Bristol-Myers Squibb, Experimental Station, E400/3227, Wilmington, DE 19880. E-mail: jeremy.toyn{at}bms.com

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Jan 2009	9	17	4
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Apr 2009	17	10	3
May 2009	5	11	5
Jun 2009	11	17	10
Jul 2009	15	16	2
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Oct 2009	2	4	23
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Jan 2010	1	5	15
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Mar 2010	4	2	16
Apr 2010	7	2	5
May 2010	6	12	3
Jun 2010	2	18	10
Jul 2010	3	9	8
Aug 2010	7	13	1
Sep 2010	13	17	5
Oct 2010	2	22	5
Nov 2010	8	18	3
Dec 2010	4	14	4
Jan 2011	6	9	4
Feb 2011	8	9	4
Mar 2011	7	15	5
Apr 2011	6	11	6
May 2011	16	11	4
Jun 2011	12	7	6
Jul 2011	5	4	5
Aug 2011	9	3	8
Sep 2011	6	4	11
Oct 2011	4	6	19
Nov 2011	8	8	12
Dec 2011	7	4	14
Jan 2012	8	11	20
Feb 2012	8	7	15
Mar 2012	9	11	17
Apr 2012	9	10	12
May 2012	9	12	12
Jun 2012	8	13	6
Jul 2012	10	19	16
Aug 2012	3	4	11
Sep 2012	9	5	13
Oct 2012	12	20	11
Nov 2012	10	9	16
Dec 2012	10	22	9
Jan 2013	21	19	11
Feb 2013	8	8	8
Mar 2013	7	9	14
Apr 2013	16	7	12
May 2013	5	7	16
Jun 2013	3	1	11
Jul 2013	5	4	4
Aug 2013	8	2	4
Sep 2013	1	2	430
Oct 2013	39	1	11
Nov 2013	14	8	12
Dec 2013	11	5	12
Jan 2014	10	3	9
Feb 2014	4	6	8
Mar 2014	3	4	9
Apr 2014	8	5	18
May 2014	14	3	11
Jun 2014	11	1	13
Jul 2014	9	10	3
Aug 2014	7	3	6
Sep 2014	13	7	21
Oct 2014	6	6	2
Nov 2014	9	11	11
Dec 2014	1	6	4
Jan 2015	1	9	15
Feb 2015	2	4	3
Mar 2015	4	4	9
Apr 2015	3	5	4
May 2015	0	1	0
Jun 2015	12	8	12
Jul 2015	5	9	25
Aug 2015	6	4	9
Sep 2015	9	4	3
Oct 2015	2	6	6
Nov 2015	6	4	4
Dec 2015	13	5	6
Jan 2016	34	13	4
Feb 2016	2	10	8
Mar 2016	3	5	6
Apr 2016	2	6	6
May 2016	5	9	7
Jun 2016	3	11	14
Jul 2016	4	20	11
Aug 2016	1	17	7
Sep 2016	0	14	8
Oct 2016	2	11	9
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Dec 2016	2	13	1
Jan 2017	3	13	9
Feb 2017	1	17	2
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Apr 2017	2	26	5
May 2017	2	33	2
Jun 2017	3	23	6
Jul 2017	0	17	1
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Oct 2017	1	10	0
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Dec 2017	2	11	2
Jan 2018	0	12	3
Feb 2018	2	17	3
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Apr 2018	6	14	5
May 2018	0	15	4
Jun 2018	2	16	5
Jul 2018	1	24	2
Aug 2018	0	29	0
Sep 2018	1	16	1
Oct 2018	3	8	11
Nov 2018	2	30	5
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Feb 2019	0	41	0
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Oct 2019	2	538	3
Nov 2019	5	349	4
Dec 2019	0	206	6
Jan 2020	1	11	4
Feb 2020	4	26	12
Mar 2020	2	8	5
Apr 2020	3	11	5
May 2020	7	14	7
Jun 2020	2	10	3
Jul 2020	1	5	5
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Oct 2020	9	7	5
Nov 2020	8	10	15
Dec 2020	4	7	3
Jan 2021	1	106	6
Feb 2021	0	7	3
Mar 2021	3	12	3
Apr 2021	1	7	4
Total	1651	6897	2327