18,409 Results
for term "sites"
- Genome-Wide Characterization of Tetrahymena thermophila Chromosome Breakage Sites. II. Physical and Genetic Mapping...) genome of Tetrahymena thermophila are generated by developmental fragmentation of the five micronuclear (germline) chromosomes. This fragmentation is site specific, directed by a conserved chromosome breakage sequence (Cbs element). An accompanying article in this issue reports the development ~~~
- Genetic Evidence for Sites of Interaction Between the Gal3 and Gal80 Proteins of the Saccharomyces cerevisiae GAL Gene Switch...). All GHMP superfamily members have conserved motifs for the binding of ATP and their specific substrates, and most have been crystallized with their substrates bound. Thus, the binding sites for galactose and ATP in galactokinase are well established. All GHMP members share a similar overall protein ~~~
- Alternative Transcription Initiation Sites and Polyadenylation Sites Are Recruited During Mu Suppression at the rf2a Locus of Maize...a novel Mu transposon insertion (Mu10) in its 5 untranslated region (UTR). The suppressible rf2a-m9390 allele has a Mu1 insertion in its 5 UTR. During suppression, alternative transcription initiation sites flanking the Mu1 transposon yield functional transcripts. The suppressible rf2a-m8110 allele has ~~~
- Loss-of-Function Alleles of the JIL-1 Histone H3S10 Kinase Enhance Position-Effect Variegation at Pericentric Sites in Drosophila Heterochromatin...Accepted for publication April 12, 2007 ABSTRACT In this study we show that loss-of-function alleles of the JIL-1 histone H3S10 kinase act as enhancers of position-effect variegation at pericentric sites whereas the gain-of-function JIL-1Su(var)3-13 allele acts as a suppressor strongly supporting ~~~
- The Distribution of Transgene Insertion Sites in Barley Determined by Physical and Genetic Mapping...received November 6, 2003 Accepted for publication April 2, 2004 ABSTRACT The exact site of transgene insertion into a plant host genome is one feature of the genetic transformation process that cannot, at present, be controlled and is often poorly understood. The site of transgene insertion may have ~~~
- Mapping Sites of Positive Selection and Amino Acid Diversification in the HIV Genome...to identify positively selected sites that are likely to be involved in the immune control of HIV-1. Analysis of subtypes B and C revealed widespread adaptive evolution. Positively selected amino acids were detected in all nine HIV-1 proteins, including Env. Of particular interest was the high level ~~~
- Properties of Natural Double-Strand-Break Sites at a Recombination Hotspot in Saccharomyces cerevisiae..., 2003 ABSTRACT This study addresses three questions about the properties of recombination hotspots in Saccharomyces cerevisiae : How much DNA is required for double-strand-break (DSB) site recognition? Do naturally occurring DSB sites compete with each other in meiotic recombination? What role does ~~~
- Effects of Natural Selection on Interpopulation Divergence at Polymorphic Sites in Human Protein-Coding Loci...was evidence of purifying selection acting at these sites, which in turn causes a reduction in interpopulation divergence. By contrast, a small number of SNP sites in these categories revealed unusually high genetic distances between the two most diverged populations (African and Asian); these loci may have ~~~
- The Enhancer-Blocking Activity of the Fab-7 Boundary From the Drosophila Bithorax Complex Requires GAGA-Factor-Binding Sites...bithorax complex (BX-C). One of the three nuclease hypersensitive sites in the Fab-7 boundary, HS1, contains multiple consensus-binding sequences for the GAGA factor, a protein known to be involved in the formation and/or maintenance of nucleosome-free regions of chromatin. GAGA protein has been shown ~~~
- Accuracy and Power of Statistical Methods for Detecting Adaptive Evolution in Protein Coding Sequences and for Identifying Positively Selected Sites...for detecting positive selection or identifying positively selected sites. MUCH attention has recently been devoted to the mony reconstruction of ancestral sequences, and an ex-detection of positive selection on protein-coding cess of nonsynonymous substitutions is tested indepenDNA sequences in molecular ~~~