14 Results
for term "sites"
- Marcus Rhoades on Preferential Segregation in Maize...on chromosome 10 induced neocentromere formation at heterochromatic knob sites across the genome, including a large one on the abnormal chromosome. These neocentromeres proceed to the poles in meiosis much faster than the canonical centromeres, causing preferential segregation of linked genes and providing ~~~
- Hubby and Lewontin on Protein Variation in Natural Populations: When Molecular Genetics Came to the Rescue of Population Genetics...nucleotide site rather than per gene (Nei 1987). The proportion of polymorphic loci (P) was also introduced. This used the arbitrary criterion that a locus should show more than a single allele among the strains or individuals studied, and is little used today, although it is related to the estimator ~~~
- Fumio Tajima and the Origin of Modern Population Genetics..., this is not the main reason Tajimas (1983) paper became so highly cited. In a later section of the paper, Tajima provided the rst derivation of the variance of the average number of pairwise differences (p) under the innite sites model, and argued in favor of using p as an estimator of the mutation scaled effective ~~~
- The Hiroshima/Nagasaki Survivor Studies: Discrepancies Between Results and General Perception...begetters of malformed offspring. While not reaching such extremes, the dominant present-day image of the aftermath of theHiroshima/ Nagasaki bombings, in line with the general perception of radiation risk (Ropeik 2013; Perko 2014), is that it left the sites heavily contaminated, that the survivors suffered ~~~
- Barbara McClintock on Defining the Unstable Genome...in maize, and the insight that led to her discovery of mobile genetic elements. While studying the behavior of broken chromosome ends during mitosis, McClintock came across a site on maize chromosome 9 thatwas sensitive to breakage. Breakage depended on an element that she named Dissociation, or Ds. She ~~~
- Charlesworth et al. on Background Selection and Neutral Diversity...in regions of low recombination rates because, in these locations, benecial mutations will be linked to a greater number of sites. This prediction set in motion empirical work that examined the distribution of neutral diversity in natural populations. Stephan and Langley (1989), Aguade et al. (1989), Begun ~~~
- Eric Lander and David Botstein on Mapping Quantitative Traits...-in-ploidy mutants in yeast. Genetics 135: 677691. Chan, R. K., and D. Botstein, 1976 Specialized transduction by bacteriophage P22 in Salmonella typhimurium: genetic and physical structure of the transducing genomes and the prophage attachment site. Genetics 83: 433458. Dietrich, W., H. Katz, S. E. Lincoln, H. S ~~~
- Navigating the Phenotype Frontier: The Monarch Initiative...across species (Figure 2.5), biological scales (Figure 2.7), and community-specic vocabularies (Figure 2.1) (Smedley et al. 2013). Monarch supports researchers and clinicians using this data with visualization tools, application programming interfaces, and a rich web site (https ~~~
- Biochemical Genetics and Molecular Biology: The Contributions of George Beadle and Edward Tatum...can code multiple peptides as a result of multiple start sites and patterns of exon use and of the nature of protein structure make it clear that single peptides may participate in numerous reactions and that single proteins may participate in numerous developmental processes. In retrospect ~~~
- Medical Genetics and the First Studies of the Genetics of Populations in Mexico...S (HbS) was typical of the Northwest and central Africa, and was found at all sites where there had been immigration of black Africans. Hemoglobin C was typical of Western Africa, while hemoglobin E was almost exclusively from Southeast Asia. Correlating these data with those obtained for Mexican ~~~