29 Results
for term "sites"
- Phylogenetic Footprinting Analysis in the Upstream Regulatory Regions of the Drosophila Enhancer of split Genes..., 2007 ABSTRACT During Drosophila development Suppressor of Hairless Su(H)#2;-dependent Notch activation upregulates transcription of the Enhancer of split-Complex E(spl)-C genes. Drosophila melanogaster E(spl) genes share common transcription regulators including binding sites for Su(H), proneural ~~~
- Molecular Evolution of Glutathione S-Transferases in the Genus Drosophila...their own unique functions or have spatial/temporal expression patterns that impose significant selective constraints. Searches for positively selected sites within the GSTs identified G171K in GSTD1, a protein that has previously been shown to be capable of metabolizing the insecticide DDT. We find ~~~
- Conservation of Epigenetic Regulation, ORC Binding and Developmental Timing of DNA Replication Origins in the Genus Drosophila...foci of different intensities after labeling with BrdU(Calvi et al. 1998). This highly selective site-specific replication represents an extreme form of origin developmental specificity, but it is currently unknownwhat coordinates this amplification phase with the development of the egg chamber ~~~
- Positive Selection Near an Inversion Breakpoint on the Neo-X Chromosome of Drosophila americana...regions in the genome sequence of D. virilis and used to screen the clone DNA as sequence tagged sites (STSs). Supplemental Table S3 (http:// www..org/supplemental/) describes each primer pair. Presence and absence of STSs in the clones localized each breakpoint to an interval between adjacent genes ~~~
- Divergence Between the Drosophila pseudoobscura and D. persimilis Genome Sequences in Relation to Chromosomal Inversions...to this work. 2Corresponding author: Biology Department, Box 90338, Duke University, Durham, NC 27708. E-mail: noor@duke.edu Genetics 177: 14171428 (November 2007) divergence, coding silent site, and intron divergence, we test whether introgression is restricted only within inverted regions or whether ~~~
- Variable Strength of Translational Selection Among 12 Drosophila Species...assume that codons are chosen randomly from all available synonymous codons, subject to nucleic acid compositional biases and to selection. A negative correlation between the number of synonymous substitutions per synonymous site, dS, and the codon usage bias of a gene has been reported and, at times ~~~
- Evolution in the Fast Lane: Rapidly Evolving Sex-Related Genes in Drosophila...) and sequence divergence using the assumption of a single nonsynonymous substitution per nonsynomous site over synonymous substitution per synonymous site ratio (v) per gene (PAML, model M0; Yang and Nielsen 2002). As previously reported in other organisms (Torgerson et al. 2002; Khaitovich et al. 2005), we ~~~
- Five Drosophila Genomes Reveal Nonneutral Evolution and the Signature of Host Specialization in the Chemoreceptor Superfamily...power. Its decomposition into two approximately equal-sized families (Ors and Grs) allows for compelling parallel studies and contrasts. And the fact that Or and Gr genes are distributed throughout the genome and do not show strong codon bias (a sign of selection on silent sites; Akashi 1994) makes them ~~~
- An Evolutionarily Conserved Domain of roX2 RNA Is Sufficient for Induction of H4-Lys16 Acetylation on the Drosophila X Chromosome...) (RNA helicase) (Meller et al. 2000). This complex has been shown to bind to hundreds of sites on the male X chromosome (Kelley et al. 1999; Meller et al. 2000) and increase its gene expression by approximately twofold through specific histone H4-Lys16 acetylation (Smith et al. 2000; Hamada et al. 2005 ~~~
- Phylogenetic and Genomewide Analyses Suggest a Functional Relationship Between kayak, the Drosophila Fos Homolog, and fig, a Predicted Protein Phosphatase 2C Nested Within a kayak Intron...there is a predicted, divergently transcribed gene (CG7615) that we have named fos intron gene (fig). Our new model determined that kay has three transcription initiation sites that create alternative 59 exons, each containing their own predicted initiator methionine (Figure 1A). Each of these 59 exons splices ~~~