18,412 Results
for term "sites"
- The Characteristic Trajectory of a Fixing Allele: A Consequence of Fictitious Selection That Arises from Conditioning...uctuations in the estimated population size at this site, the trajectory ts well with expectations that are based on a constant positive selection coefcient; explorations of multiple populations throughout England also found trajectories that are consistent with constant selection during xation ~~~
- The Drosophila wings apart Gene Anchors a Novel, Evolutionarily Conserved Pathway of Neuromuscular Development...for expression of the eo gene product or some key regulatory region is not duplicated by the duplication line being tested. It was not surprising that the uncl mutation could not be rescued by any of the duplications, since the results from the deciency screen suggested that multiple sites on the X chromosome ~~~
- Association of Polymorphisms in Odorant-Binding Protein Genes With Variation in Olfactory Response to Benzaldehyde in Drosophila...threshold for association with responsiveness to benzaldehyde, suggesting redundancy and/or combinatorial recognition by these OBPs of this odorant. Model predictions of alternative pre-mRNA secondary structures associated with polymorphic sites suggest that alterations in Obp mRNA structure could ~~~
- Rates of Recombination in the Ribosomal DNA of Apomictically Propagated Daphnia obtusa Lines...the production of meiotically produced haploid diapausing eggs that require fertilization by males. An analysis of restriction site polymorphism has shown that organisms that reproduce parthenogenetically have highly homogenized rDNA repeats, demonstrating that the frequency of recombination events during germ ~~~
- New Experiments for an Undivided Genetics...endogenous conditions such as diabetes, hypertension, obesity, and other ailments that are longsustained and not direct outcomes of infection. Genome-wide association (GWA) studies use highthroughput methods to genotype panels of individuals at hundreds of thousands of sites and relate those sites to traits ~~~
- Gene Expression Intensity Shapes Evolutionary Rates of the Proteins Encoded by the Vertebrate Genome...explanation of selection on individual amino acid our Precambrian animal ancestor? The answer to this sites to ensure protein function (Li 1997; Nei and Kumar question may provide insight into the mechanisms re2000). Examination of the relationship of the rate of sponsible for evolution of animal complexity ~~~
- Reduced X-Linked Diversity in Derived Populations of House Mice...not significantly differ (average 13.7 vs. 11.3 genes/Mb, respectively, MannWhitney U-test; P 0.351). Thus, the loci should experience roughly equal opportunity for selection at linked sites. In addition, we note that one autosomal locus, Ggh, which was clearly present as single copy in all NCBI builds prior ~~~
- A Sensitized PiggyBac-Based Screen for Regulators of Border Cell Migration in Drosophila...mapping of novel PBac insertions: DNA was prepared using the DNAeasy kit (QIAGEN, Chatsworth, CA), and inverse PCR and DNA sequencing were performed as described in Hacker et al. (2003). Generation of constructs: PiggyBac vector: A NheI site was cloned in place of the PstI site in pPBac{3xP3-EGFPaf} (Horn ~~~
- The Yeast Histone Chaperone Chromatin Assembly Factor 1 Protects Against Double-Strand DNA-Damaging Agents...viability. Furthermore, CAF-1 is not required for repair of the DNA per se or for DNA damage checkpoint function. CAF-1mediated resistance to DNA damage is dependent on the ability of CAF-1 to bind PCNA, indicating that PCNA may recruit CAF-1 to sites of double-strand DNA repair. We propose that CAF-1 has ~~~