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  • Freedom and Responsibility in Synthetic Genomics: The Synthetic Yeast Project
    Anna Sliva, Huanming Yang, Jef D. Boeke, Debra J. H. Mathews
    Genetics August 2015 200: 1021-1028; https://doi.org/10.1534/genetics.115.176370
    .... These engineered features will be used as tools to answer a number of age-old biological questions. Two of these genome-wide genetic tools are (1) symmetrical loxP sites, introduced throughout the genome, which will be used in genome structure/evolution experiments, and (2) the swapping out of all TAG with TAA ~~~
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