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  • Association of Polymorphisms in Odorant-Binding Protein Genes With Variation in Olfactory Response to Benzaldehyde in Drosophila
    Ping Wang, Richard F. Lyman, Svetlana A. Shabalina, Trudy F. C. Mackay, Robert R. H. Anholt
    Genetics November 2007 177: 1655-1665; https://doi.org/10.1534/genetics.107.079731
    ...threshold for association with responsiveness to benzaldehyde, suggesting redundancy and/or combinatorial recognition by these OBPs of this odorant. Model predictions of alternative pre-mRNA secondary structures associated with polymorphic sites suggest that alterations in Obp mRNA structure could ~~~
  • Rates of Recombination in the Ribosomal DNA of Apomictically Propagated Daphnia obtusa Lines
    Seanna J. McTaggart, Jeffry L. Dudycha, Angela Omilian, Teresa J. Crease
    Genetics January 2007 175: 311-320; https://doi.org/10.1534/genetics.105.050229
    ...the production of meiotically produced haploid diapausing eggs that require fertilization by males. An analysis of restriction site polymorphism has shown that organisms that reproduce parthenogenetically have highly homogenized rDNA repeats, demonstrating that the frequency of recombination events during germ ~~~
  • New Experiments for an Undivided Genetics
    Michael R. Rose, Laurence D. Mueller, Molly K. Burke
    Genetics May 2011 188: 1-10; https://doi.org/10.1534/genetics.111.128900
    ...endogenous conditions such as diabetes, hypertension, obesity, and other ailments that are longsustained and not direct outcomes of infection. Genome-wide association (GWA) studies use highthroughput methods to genotype panels of individuals at hundreds of thousands of sites and relate those sites to traits ~~~
  • Gene Expression Intensity Shapes Evolutionary Rates of the Proteins Encoded by the Vertebrate Genome
    Sankar Subramanian, Sudhir Kumar
    Genetics September 2004 168: 373-381; https://doi.org/10.1534/genetics.104.028944
    ...explanation of selection on individual amino acid our Precambrian animal ancestor? The answer to this sites to ensure protein function (Li 1997; Nei and Kumar question may provide insight into the mechanisms re2000). Examination of the relationship of the rate of sponsible for evolution of animal complexity ~~~
  • Reduced X-Linked Diversity in Derived Populations of House Mice
    John F. Baines, Bettina Harr
    Genetics April 2007 175: 1911-1921; https://doi.org/10.1534/genetics.106.069419
    ...not significantly differ (average 13.7 vs. 11.3 genes/Mb, respectively, MannWhitney U-test; P 0.351). Thus, the loci should experience roughly equal opportunity for selection at linked sites. In addition, we note that one autosomal locus, Ggh, which was clearly present as single copy in all NCBI builds prior ~~~
  • A Sensitized PiggyBac-Based Screen for Regulators of Border Cell Migration in Drosophila
    Juliette Mathieu, Hsin-Ho Sung, Céline Pugieux, Jan Soetaert, Pernille Rorth
    Genetics July 2007 176: 1579-1590; https://doi.org/10.1534/genetics.107.071282
    ...mapping of novel PBac insertions: DNA was prepared using the DNAeasy kit (QIAGEN, Chatsworth, CA), and inverse PCR and DNA sequencing were performed as described in Hacker et al. (2003). Generation of constructs: PiggyBac vector: A NheI site was cloned in place of the PstI site in pPBac{3xP3-EGFPaf} (Horn ~~~
  • The Yeast Histone Chaperone Chromatin Assembly Factor 1 Protects Against Double-Strand DNA-Damaging Agents
    Jeffrey Linger, Jessica K. Tyler
    Genetics December 2005 171: 1513-1522; https://doi.org/10.1534/genetics.105.043000
    ...viability. Furthermore, CAF-1 is not required for repair of the DNA per se or for DNA damage checkpoint function. CAF-1mediated resistance to DNA damage is dependent on the ability of CAF-1 to bind PCNA, indicating that PCNA may recruit CAF-1 to sites of double-strand DNA repair. We propose that CAF-1 has ~~~
  • The Cik1/Kar3 Motor Complex Is Required for the Proper Kinetochore–Microtubule Interaction After Stressful DNA Replication
    Hong Liu, Fengzhi Jin, Fengshan Liang, Xuemei Tian, Yanchang Wang
    Genetics February 2011 187: 397-407; https://doi.org/10.1534/genetics.110.125468
    ...ACC ATC GAT GGT GCG GTT GAT TCG TTT TAT A39). The forward and reverse primers contain SacII and ClaI restriction enzyme sites, respectively. The PCR products and pRS416 vector were digested with both SacII and ClaI (Sikorski and Hieter 1989). After recovery from the agarose gel, the fragments were ~~~
  • The Putative Lipid Transporter, Arv1, Is Required for Activating Pheromone-Induced MAP Kinase Signaling in Saccharomyces cerevisiae
    Michelle L. Villasmil, Alison Ansbach, Joseph T. Nickels
    Genetics February 2011 187: 455-465; https://doi.org/10.1534/genetics.110.120725
    ..., which allows for polarized cell growth and alterations in nuclear architecture, ultimately leading to cell fusion and formation of an a/a diploid (Wang and Dohlman 2004). In S. cerevisiae, pheromones stimulate the formation and growth of mating projections called shmoos. The site of polarization ~~~
  • fastSTRUCTURE: Variational Inference of Population Structure in Large SNP Data Sets
    Anil Raj, Matthew Stephens, Jonathan K. Pritchard
    Genetics June 2014 197: 573-589; https://doi.org/10.1534/genetics.114.164350

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GSA

The Genetics Society of America (GSA), founded in 1931, is the professional membership organization for scientific researchers and educators in the field of genetics. Our members work to advance knowledge in the basic mechanisms of inheritance, from the molecular to the population level.

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