17 Results
for term "sites"
- Mapping Yeast Transcriptional Networks...using terminology adapted from graph theory (e.g., Balaji et al. 2006; Yu and Gerstein 2006; Michoel et al. 2011); the relationships among TF binding sites, TF binding events, gene expression patterns, and gene functions (e.g., Gao et al. 2004; Hu et al. 2007); and inferred (or reconstructed ~~~
- Ribosome Biogenesis in the Yeast Saccharomyces cerevisiae...). Comparison of these eukaryotic ribosome structures with those of bacterial and archaeal ribosomes reveals a universally conserved structural core (Melnikov et al. 2012) that contains the sites for ribosome functions: the peptidyltransferase center, the polypeptide exit tunnel, and the GTPase binding site ~~~
- RNA Degradation in Saccharomyces cerevisae...Xrn1 or nuclear Rat1 59 to 39 nucleases, or to the exosome, which is a conserved cytoplasmic and nuclear complex with both 39 to 59 exonuclease activities and an endonuclease cleavage site. Second, where examined, all RNAs are subject to quality control systems where nonfunctional RNAs are more ~~~
- Transcriptional Regulation in Saccharomyces cerevisiae: Transcription Factor Regulation and Function, Mechanisms of Initiation, and Roles of Activators and Coactivators...98109. E-mail: shahn@fhcrc.org Genetics, Vol. 189, 705736 November 2011 705 CONTENTS, continued Leu3 binding to a metabolite activates transcription 712 Zap1: AD regulation by Zn+2 binding 713 Core Promoter Architecture 713 Two promoter assembly pathways 714 Transcription start site determinants 714 ~~~
- Chromatin and Transcription in Yeast..., nuclease studies of the PHO5 and GAL110 genes (reviewed in Lohr 1997 and described below) established the principle that nucleosomes are found over promoters when the genes are repressed, blocking access of transcription factors to their binding sites, and that nucleosomes are altered or removed upon ~~~
- Transfer RNA Post-Transcriptional Processing, Turnover, and Subcellular Dynamics in the Yeast Saccharomyces cerevisiae...isoforms. Cca1I, Cca1-II, and Cca1-III are generated by alternative transcriptional and translational start sites. These isoforms are differently distributed among mitochondria, the cytoplasm, and the nucleoplasm (reviewed in Martin and Hopper 1994). The nuclear pool functions in tRNA 39 end biogenesis ~~~
- Nutritional Control of Growth and Development in Yeast...response to glucose but the indicated link is only speculative. Red dots signify phosphorylation. How Yeast Respond to Nutrients 77 on two-hybrid interaction. However, substantial evidence has accumulated discounting Gpb1/Gpb2 as b subunits (Peeters et al. 2007), including the fact that the site on Gpa2 ~~~
- Regulation of Amino Acid, Nucleotide, and Phosphate Metabolism in Saccharomyces cerevisiae...in the presence of repressing nitrogen sources. Consistent with this latter nding, GZF3 expression is induced by Gat1 under conditions when Gln3 is apparently inactive (Rowen et al. 1997). Gzf3 maintains low levels of GAT1 expression by competing with Gat1 at GATAAG-binding sites; in essence, these two factors ~~~
Figure 1Regulation of the PHO5 gene. Shown are diagrams of PHO5 when repressed (top) and induced (bottom). In the repressed state (high phosphate), four nucleosomes (−4 to −1, shown in light blue) span the PHO5 regulatory region, including nucleosome −2, which blocks one of the Pho4-bindings sites (red line). Several factors, shown on the left and described in the text, are required for PHO5 induction, which results in loss of nucleosomes over the PHO5 regulatory region, the binding of Pho4, and activation of transcription. The dotted lines around nucleosomes −4 and −1 indicate a more variable degree of loss. Upon addition of phosphate, the nucleosomes reassemble in the PHO5 regulatory region in an Spt6-dependent fashion, resulting in transcriptional repression.