318 Results
for term "sites"
- Stable Binding of the Conserved Transcription Factor Grainy Head to its Target Genes Throughout Drosophila melanogaster Development...2010; Spitz and Furlong 2012; Yanez-Cuna et al. 2012; Slattery et al. 2013, 2014). These changes in binding site occupancy by sequence-specic transcription factors are regulated largely through alterations in chromatin structure that modulate the accessible regions of the genome (Kaplan et al. 2011 ~~~
- Different Evolutionary Strategies To Conserve Chromatin Boundary Function in the Bithorax Complex.... Moreover, the ability of the su(Hw) insulator to prevent crosstalk between iab-6 and iab-7 is tissue specic, and is lost in the embryonic CNS. The Fab-7 insulator has also been replaced with multimerized dCTCF sites and boundaries from BX-C (Kyrchanova et al. 2016). Surprisingly, only Fab-8 was able ~~~
- The Role of +4U as an Extended Translation Termination Signal in Bacteria...-cognate tRNAs that decode codons differing from UAA by a single nucleotide), particularly those with a mismatch at the rst stop codon site. UAA is always the preferred stop codon in HEGs, and our results suggest that UAAU is the most efcient translation termination signal in bacteria. KEYWORDS translation ~~~
- Multiple Transcriptional and Post-transcriptional Pathways Collaborate to Control Sense and Antisense RNAs of Tf2 Retroelements in Fission Yeast...conrmed the signicant increase in Tf2 mRNA in the pab2D mutant (Figure 1, A and B). Analysis of Tf2 transcription start sites by 59 RACE in the pab2 mutant generally mapped to 180-nt from the 59 end of the LTR, which is consistent with previous observations (Rhind et al. 2011; Persson et al. 2016 ~~~
- General Amino Acid Control and 14-3-3 Proteins Bmh1/2 Are Required for Nitrogen Catabolite Repression-Sensitive Regulation of Gln3 and Gat1 Localization...-rich yeast nitrogen base (YNB)-glutamine medium, accompanied by the characteristic tripartite distribution, but without further effects (Rai et al. 2016). When the alanine substitutions in Gln3477497 (pRR680) were combined by those in the Gln3-mTor1 interaction site (pRR850), they additively eliminated ~~~
- The Promiscuous sumA Missense Suppressor from Salmonella enterica Has an Intriguing Mechanism of Action..., a primer that sequences outwards from the end of the chloramphenicol resistance region from pACYC184. The site of the Tn10dTet insertion that was 99% linked to sumA was determined to be at bp 4,596,266 of the S. enterica chromosome (McClelland et al. 2001, GenBank accession number NC_003197). Since the gly ~~~
- An Unexpected Regulatory Cascade Governs a Core Function of the Drosophila PRC1 Chromatin Protein Su(z)2...48: 10542 10548. Bodenmiller, B., D. Campbell, B. Gerrits, H. Lam, M. Jovanovic et al., 2008 PhosphoPep: a database of protein phosphorylation sites in model organisms. Nat. Biotechnol. 26: 13391340. Brunk, B. P., E. C. Martin, and P. N. Adler, 1991 Drosophila genes posterior sex combs ~~~
- A Cre Transcription Fidelity Reporter Identifies GreA as a Major RNA Proofreading Factor in Escherichia coli...The construction of the galK-loxP-INV reporter system is shown in Figure S1 in File S1. The galK gene is highly conserved from E. coli to humans. Alignment of all GalK protein homologs revealed regions of the protein that are not conserved. We focused on one of these regions. At a site located between amino acid ~~~
- Comprehensive Analysis of the SUL1 Promoter of Saccharomyces cerevisiae....4%. Combinations of these benecial mutations increased tness only up to 11%. Thus, in the case of SUL1, promoter mutations could not induce a tness increase similar to that of gene amplication. Using these data, we identied functionally important regions of the SUL1 promoter and analyzed three sites ~~~