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  • Mitotic Exit and Separation of Mother and Daughter Cells
    Eric L. Weiss
    Genetics December 2012 192: 1165-1202; https://doi.org/10.1534/genetics.112.145516
    ...network 1181 Overview: 1181 RAM components: the Mob2Cbk1 module: 1181 RAM components: the Kic1Hym1 module: 1183 RAM components: Tao3 and Sog2: 1183 Functional organization of the RAM network: 1183 Regulatory phosphorylation of Cbk1s hydrophobic motif site and activation loop: 1184 The RAM network ~~~
  • Cell Polarization and Cytokinesis in Budding Yeast
    Erfei Bi, Hay-Oak Park
    Genetics June 2012 191: 347-387; https://doi.org/10.1534/genetics.111.132886
    ...: 364 Mechanism of Cytokinesis 364 Actomyosin ring assembly and disassembly 365 AMR assembly: 365 A model and key questions on AMR assembly: 367 AMR disassembly: 367 Targeted membrane deposition and primary septum formation 368 Polarized exocytosis and membrane addition at the division site: 368 ~~~
  • Regulation of Cell Wall Biogenesis in Saccharomyces cerevisiae: The Cell Wall Integrity Signaling Pathway
    David E. Levin, P. Pryciak
    Genetics December 2011 189: 1145-1175; https://doi.org/10.1534/genetics.111.128264
    ...of the cell wall, as well as their polarized delivery to the site of cell wall remodeling. This review article centers on CWI signaling in Saccharomyces cerevisiae through the cell cycle and in response to cell wall stress. The interface of this signaling pathway with other pathways that contribute ~~~
  • Mating-Type Genes and MAT Switching in Saccharomyces cerevisiae
    James E. Haber
    Genetics May 2012 191: 33-64; https://doi.org/10.1534/genetics.111.134577
    ...their mating type as often as every generation by a highly choreographed, site-specic homologous recombination event that replaces one MAT allele with different DNA sequences encoding the opposite MAT allele. This replacement process involves the participation of two intact but unexpressed copies of mating ~~~
  • Architecture and Biosynthesis of the Saccharomyces cerevisiae Cell Wall
    Peter Orlean
    Genetics November 2012 192: 775-818; https://doi.org/10.1534/genetics.112.144485
    ...-X-Thr over Asn-X-Ser sites (Schulz and Aebi 2009). Analyses of protein-linked N-glycans in mutants defective in the elaboration of the Dol-PP-linked precursor indicate that structures smaller than GlcNAc2Man9Glc3 can be transferred in vivo. Yeast OST consists of Stt3, Ost1, Ost2, Wbp1, Swp1, Ost4, Ost5 ~~~
  • Response to Hyperosmotic Stress
    Haruo Saito, Francesc Posas
    Genetics October 2012 192: 289-318; https://doi.org/10.1534/genetics.112.140863
    ..., and a histidine auto-phosphorylation site, and the second is a response regulator (RR) that contains an output (or effector) domain and a receiver (REC) domain. When the input domain senses a relevant stimulus, the HK is activated (or inactivated), and a histidine residue located near the HK domain ~~~
  • Regulation of Cation Balance in Saccharomyces cerevisiae
    Martha S. Cyert, Caroline C. Philpott
    Genetics March 2013 193: 677-713; https://doi.org/10.1534/genetics.112.147207
    ...to associate into a homotetramer. Trk1/2-mediated transport displays high afnity for K+ and Rb+, and high velocity (Vmax = 30 nmol/mg cells/min) that is driven by the negative electrochemical potential established by the H+-APTase (Rodriguez-Navarro and Ramos 1984). Each transporter has two binding sites ~~~
  • Sporulation in the Budding Yeast Saccharomyces cerevisiae
    Aaron M. Neiman, P. Pryciak
    Genetics November 2011 189: 737-765; https://doi.org/10.1534/genetics.111.127126
    ...the meiotic divisions give rise to four haploid nuclei that are then packaged into daughter cells (Figure 1A). This packaging requires a host of changes in the cell cytoplasm. Initially, the four spindle pole bodies (SPBs) present in meiosis II are modied so that they become the sites of formation for new ~~~
  • The Regulation of Filamentous Growth in Yeast
    Paul J. Cullen, George F. Sprague, P. Pryciak
    Genetics January 2012 190: 23-49; https://doi.org/10.1534/genetics.111.127456
    ...by the occulin Flo11 37 Cell polarity reorganization by bud-siteselection proteins 38 Cell elongation due to changes in the cell cycle and polarized growth 40 Transcriptional targets of lamentation signaling pathways 40 Perspectives 41 FILAMENTOUS growth is a fungal differentiation behaviorthat occurs ~~~
  • Target of Rapamycin (TOR) in Nutrient Signaling and Growth Control
    Robbie Loewith, Michael N. Hall, J. Thorner
    Genetics December 2011 189: 1177-1201; https://doi.org/10.1534/genetics.111.133363
    .... They not only identied TOR, but also identied the FKBPrapamycinbinding site in TOR and contributed to elucidating the mechanism of action of rapamycin. The kinase domain is the catalytic domain and resembles the kinase domain of PI3K and PI4K lipid kinases. Despite high interest in a structure of the kinase ~~~

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