6 Results
for term "sites"
- The foundations of genetic fine structure: a retrospective from memory....and its functional allele asteroid (ast, then sr or Star reces- sive) occupied separate but contiguous chromosomal sites and therefore should be separable by crossing over. He set out to do this by looking for wild-type recombinants. The l z situation is a classical example of the BATESON ~~~
- Studies of yeast cytochrome c: how and why they started and why they continued....sequence of iso-1-cytochrome c was reported by NARITA et al. (1963), numerous cycl mutations were identified, their sites were determined by deletion mapping and, in collaboration with J. STEWART, their DNA se- quences were deduced from the amino acid alterations in revertant proteins (SHERMAN and STEWART ~~~
- Barbara McClintock (June 16, 1902-September 2, 1992)....between the instability of ring-shaped chromosomes and phenotypic variegation, the discov- ery that the centromere is divisible, and the identifi- cation of a chromosomal site essential for the forma- tion of the nucleolus. In the years following completion of her doctoral work, MCCLINTOCK continued her ~~~
- Intragenic recombination in Drosophila: the rosy locus....mutations representing a single com- plementation group. Utilizing a selective system to facilitate large-scale sampling, the resolving power of such recombination permitted the elaboration of a linear order of sites within a single gene, quite com- parable to that seen in prokaryotes and fungi. The second ~~~
- The evolution of somatic selection: the antibody tale....or another, the antigen or hapten served as a template for the folding of the antibodycombining site. An outstanding example was the proposal of PAULINC (1940). Within the 10-year period from 1959 to 1969, the whole picture changed. Immunology was thrust into prominence as a source of ideas [see EDELMAN ~~~
- Forty years ago in "Genetics": the unorthodox mating behavior of bacteria....chromosome at a specific site, losing the capacity to infect by cell-to-cell contact but acquiring the property of high-frequency recombina- tion. We communicated this finding to the Bellagio 1953 International Congress of Genetics together with the first information on recombination and fit- ness (CAVALLI ~~~

