5 Results
for term "sites"
- In Memoriam: Norton Zinder (1929–2012) Geneticist...biotechnology achievements such as phage display and, more recently, the nano-battery. Having determined (via mutants, of course) that two sites on double-stranded f1 replicative form DNA made it susceptible to the B restriction system described by Werner Arber and colleagues (Arber and Linn 1969), Zinder ~~~
- In Memoriam Geoffrey W. Grigg (1926–2008)...the significance of the proposal (by Holliday, Pugh and Riggs in 1975) that cytosine methylation in DNA might control gene expression and provide a new mechanism of inheritance. In the early experiments in this field, only a subset of methylation sites could be detected. In a later visit to the LMB in 1988 ~~~
- Barbara McClintock (June 16, 1902-September 2, 1992)....between the instability of ring-shaped chromosomes and phenotypic variegation, the discov- ery that the centromere is divisible, and the identifi- cation of a chromosomal site essential for the forma- tion of the nucleolus. In the years following completion of her doctoral work, MCCLINTOCK continued her ~~~
- Motoo Kimura (1924-1994)...., widely used in population , the infinite allele, the infinite site, and the lad- der models. I was associated with some of the work mentioned in these two paragraphs, a source of deep satisfaction to me, for I could never have done the mathematics alone. I shall not list KIMURAS papers ~~~
- Charlotte Auerbach (1899-1994)....poorly if at all with DEB and other alkylating agents. Many of us privately thought that this was a consequence of an unreactive base pair at the site of the mutation, but at that time we had no way of demonstrating whether this was correct or not. LOTTE, in contrast, always believed that if she could ~~~

