45 Results
for author "Momiao Xiong"
- Table 1Association analysis of T2D status in eight European cohorts by heterogeneous Rao’s efficient score test statistics (Het-Rao), Het-MetaSKAT-O, and Het-MetaSKAT
- Table 2Association analysis of T2D status in eight European cohorts by homogeneous Rao’s efficient score test statistics (Hom-Rao), Hom-MetaSKAT-O, and Hom-MetaSKAT
- Table 3Simulation study settings
- Table 4Simulation parameter settings
- Table 5Empirical type I error rates of Rao’s efficient score test statistics and LRT statistics at different α levels based on 106 simulated data sets when only rare variants were used to generate genotype data
- Table 6Empirical type I error rates of Rao’s efficient score test statistics and LRT statistics at different α levels based on 106 simulated data sets when all variants were used to generate genotype data
Figure 1The empirical power of the GFLM Hom-Rao of models (3) and (6) as well as the AEM Het-Rao of the additive-effect model (1) and MetaSKAT atwhen some causal variants are rare and some are common and the genetic effect is simulated as homogeneous. When Neg pct = 0, all causal variants had positive effects; when Neg pct = 20, 20/80% of causal variants had negative/positive effects; when Neg pct = 50, 50/50% of causal variants had negative/positive effects.
Figure 2The empirical power of the GFLM Hom-Rao of models (3) and (6) as well as the AEM Het-Rao of the additive-effect model (1) and MetaSKAT at
Figure 3The empirical power of the GFLM Hom-Rao of models (3) and (6) as well as the AEM Het-Rao of the additive-effect model (1) and MetaSKAT at