Table 1 Genes involved in pairing and synapsis
Gene symbolCommon name (homolog)FunctionaReferences
klaroidSUN domain proteinInner nuclear membrane proteinChristophorou et al. (2015)
klarsichtKASH domainOuter nuclear member proteinChristophorou et al. (2015)
dhcDynein heavy chainMinus-end-directed motorChristophorou et al. (2015)
Chromosome axis
smc1Smc1Core cohesion componentKhetani and Bickel (2007); Gyuricza et al. (2016)
smc3Smc3Core cohesion componentKhetani and Bickel (2007); Gyuricza et al. (2016)
ordCohesion: Ord complexBickel et al. (1996), (2002); Gyuricza et al. (2016)
sunnStromalin-relatedCohesion: Ord complexKrishnan et al. (2014); Gyuricza et al. (2016)
soloCohesion: Ord complexYan and McKee (2013); Gyuricza et al. (2016)
SAStromalinCohesion: C(2)M complexGyuricza et al. (2016)
NipBSCC2Cohesion: C(2)M complexGyuricza et al. (2016)
rad21/vtdSCC1CohesionUrban et al. (2014)
SC lateral element
c(2)MKleisin-like protein; cohesion: C(2)M complexManheim and McKim (2003); Heidmann et al. (2004); Gyuricza et al. (2016); Cahoon et al. (2017)
SC central region
c(3)GZip1/SCP1Transverse filamentHall (1972); Page and Hawley (2001); Cahoon et al. (2017)
corollaTransverse filament-like proteinCollins et al. (2014); Cahoon et al. (2017)
conaCentral elementPage et al. (2008); Lake and Hawley (2012); Cahoon et al. (2017)
  • SUN, Sad1p, UNC-84; KASH, Klarsicht, ANC-1, Syne homology; SC, synaptonemal complex.

  • a Most likely function based on genetic, biochemical, or cytological data.