Table 2 PTMs and the corresponding enzymes in Drosophila gametogenesis
PTMWriterReaderEraserFunctionReference
H3K4(me)dset1, trr, trx, and ash1Phf7lid, Su(var)3-3 (lsd1)Commonly associated with promoters of actively transcribed geneBeisel et al. (2002), Sedkov et al. (2003), Di Stefano et al. (2007), Hallson et al. (2012), Yang et al. (2012), Tarayrah et al. (2015)
H3K9(me)Su(var)3-9, eggless/dSETDb1, dG9aRhino (HP1d), HP1a, HP1b, HP1edKDM4BA mark of constitute and facultative heterochromatin, functions in the maintenance of pericentric heterochromatinTschiersch et al. (1994), Ebert et al. (2006), Mis et al. (2006), Stabell et al. (2006), Levine et al. (2015)
H3K23(acetyl)enokN.D.N.D.Promotes gene expressionScott et al. (2001), Huang et al. (2014)
H3K27(me)E(z)PcdUTXAssociated with inactive gene promoters, indexing both pericentric heterochromatin and inactive euchromatic domainsMin et al. (2003), Ebert et al. (2004), Tarayrah et al. (2013)
H2A (Ub)dRingN.D.PR-DUB (calypso/Asx)Promotes repressive chromatinWang et al. (2004), Scheuermann et al. (2010)
H2B(Ub)dBre1N.D.ScrawnyEnhances nucleosome stability and mediates H3k4(me)Buszczak et al. (2009), Xuan et al. (2013)