% variance retained in (denoted by p) | Case–control sampling | Random sampling |
---|---|---|

Joint test | ||

p = 100% | 0.052 (0.0070)^{a} | 0.025 (0.0049) |

p = 99% | 0.052 (0.0070) | 0.052 (0.0070) |

G×E test | ||

p = 100% | 0.036 (0.0059) | 0.024 (0.0048) |

p = 99% | 0.047 (0.0067) | 0.043 (0.0064) |

G×E test | ||

p = 99% with 20 causal G SNPs | 0.064 (0.0077) | 0.046 (0.0066) |

p = 99% with 40 causal G SNPs | 0.049 (0.0068) | 0.046 (0.0066) |

p = 99% with 60 causal G SNPs | 0.045 (0.0066) | 0.043 (0.0064) |

p = 99% with 80 causal G SNPs | 0.050 (0.0069) | 0.042 (0.0063) |

p = 99% with 100 causal G SNPs | 0.041 (0.0063) | 0.045 (0.0066) |

The corresponding standard errors (SEs) are shown in parentheses. The values in italics are those whose 95% confidence intervals (

*i.e.*, rate ) fall below the nominal level. The results are based on 1000 replications. and are the group PARs of the genetic main effect and the*G*×*E*effect, respectively.↵a Standard errors of the type I error rates.