Table 1 Genes identified in screens for endocytosis mutants
GeneOfficial name:Also known asScreenReference
END1PEP5VAM1, VPL9, VPS11, VPT11, YMR231wLucifer yellow internalization defectChvatchko et al. (1986)
END2GAA1YLR088w(EMS mutagenesis)
END3END3YNL084cα-Factor uptake defectRaths et al. (1993)
END4SLA2MOP2, YNL243w, RCB432(EMS mutagenesis)
END5VRP1MDP2, YLR337wMunn et al. (1995)
END6RVS161FUS7, SPE161, YCR009c
END7ACT1ABY1, YFL039c
END8LCB1TSC2, YMR296cSynthetic lethal with V-ATPase mutationMunn and Riezman (1994)
END9ARC35YNR035c(EMS mutagenesis)
END10UnknownUnknown
END11ERG2YMR202w
END12VPS34PEP15, VPL7, VPT29, STT8, VPS7, YLR240w
END13VPS4CSC1, GRD13, VPL4, VPT10, DID6, YPR173c
DIM1SHE4YOR035cFM4-64 uptake defectWendland et al. (1996)
DIM2PAN1MDP3, MIP3, YIR006c(EMS mutagenesis)
DIM4FAB1SVL7, YFR019wShaw et al. (2003)
SYS1SYS1YJL004cReduced Lucifer Yellow accumulationWiederkehr et al. (2001)
YNL177cMRPL22YNL177c(Nonessential gene deletion collection)
YNL227cJJJ1YNL227c
EDE1EDE1BUD15, YBL047c
TLG2TLG2YOL018c
RCY1RCY1YJL204c
YNR075wCOS10YNR075w
SDS24SDS24YBR214w
YDR036cEHD3YDR036c
FTH1FTH1YBR207w
YBR266cREI1?YBR267w? (YBR266c = dubious ORF)
YDL231cBRE4YDL231c
YNL297cMON2YSL2, YNL297c
VPS53VPS53YJL029c
YPK1YPK1SLI2, YKL126wUbiquitin-dependent internalization of alpha-factorDehart et al. (2002)
TOR2TOR2DRR2, YKL203c(EMS mutagenesis of strain with Ste2-378Stop)Dehart et al. (2003)
A partial list of hits from the screen (only genes predicted to be involved in endocytosis)
GeneOfficial nameAlso known asRankScreenReference
RVS161RVS161END6, FUS7, SPE161, YCR009c1Elevated Snc1 levels at plasma membraneBurston et al. (2009)
VRP1VRP1END5, MDP2, YLR337w4(Nonessential gene deletion collection)
RVS167RVS167YDR388w8
LDB17LDB17YDL146w10
SLA1SLA1YBL007c12
ARC18ARC18YLR370c18
YAP1801YAP1801YHR161c29
EDE1EDE1BUD15, YBL047c31
YAP1802YAP1802YGR241c42
CAP1CAP1YKL007w45
TPM1TPM1YNL079c52
ABP1ABP1YCR088w54
MYO5MYO5YMR109w61
INP52INP52SJL2, YNL106c68
AIM21AIM21YIR003w78
CAP2CAP2YIL034c127
TWF1TWF1YGR080w155
SAC6SAC6ABP67, YDR129c209
SYP1SYP1YCR030c, YCR029c-A216
BBC1BBC1MTI1, YJL021c231
ENT1ENT1YDL161w281
END3END3YNL084c315
LSB3LSB3YFR024c-A, YFR024c338
CRN1CRN1YLR429w365
AIP1AIP1YMR092c368
BZZ1BZZ1LSB7, YHR114w383
PKH2PKH2YOL100w396
A partial list of hits from the screen (only those genes associated with endocytosis based on gene ontology are included)
APL1APL1YAP80, YJR005wKiller toxin resistanceCarroll et al. (2009)
APL3APL3YBL037w(Nonessential gene deletion + ts allele collection)
APM4APM4AMP1, YOL062c
APS2APS2YAP17, YJR058c
EDE1EDE1BUD15, YBL047c
SLA1SLA1YBL007c
SLA2SLA2END4, MOP2, YNL243w, RCB432
END3END3YNL084c
SHE4SHE4DIM1, YOR035c
VRP1VRP1END5, MDP2, YLR337w
MYO5MYO5YMR109w
ABP1ABP1YCR088w
ARC18ARC18YLR370c
SAC6SAC6ABP67, YDR129c
RVS161RVS161END6, FUS7, SPE161, YCR009c
RVS167RVS167YDR388w
APP1APP1YNL094w
SRV2SRV2CAP, YNL138w
DRS2DRS2FUN38, SWA3, YAL026c
YPK1YPK1SLI2, YKL126w
ARV1ARV1YLR242c