Sampling parameters | α | ||||||||
---|---|---|---|---|---|---|---|---|---|
N | T | L | ∆ | Absorption probability | Ň/N | 0.05 | 0.01 | 0.001 | 0.0001 |
104 | 10 | 10 | 1 | 2.6 × 10−3 | 1.3 | 1.4 | 1.7 | 2.3 | 3.3 |
104 | 100 | 10 | 10 | 7.9 × 10−4 | 1.3 | 1.4 | 1.7 | 2.3 | 2.9 |
104 | 1000 | 10 | 100 | 1.2 × 10−3 | 1.3 | 1.6 | 2.4 | 4.3 | 8.1 |
103 | 100 | 10 | 10 | 2.2 × 10−3 | 1.3 | 1.7 | 2.5 | 4.5 | 8.3 |
104 | 1000 | 10 | 100 | 1.2 × 10−3 | 1.3 | 1.6 | 2.4 | 4.3 | 8.1 |
105 | 10000 | 10 | 1000 | 1.3 × 10−2 | 1.3 | 1.2 | 1.5 | 2.3 | 3.6 |
104 | 100 | 5 | 20 | 7.7 × 10−4 | 1.7 | 2.0 | 2.9 | 5.2 | 8.5 |
104 | 100 | 10 | 10 | 7.9 × 10−4 | 1.3 | 1.4 | 1.7 | 2.3 | 2.9 |
104 | 100 | 100 | 1 | 8.0 × 10−4 | 1.0 | 1.1 | 1.1 | 1.2 | 1.4 |
Columns 1–4 show simulation and sampling parameters (see text for notations). Column 5 shows the probability that the allele fixes or goes extinct within the sampling period. Column 6 shows the ratio of the population size most likely under the neutral null hypothesis Ň to the true population size N. Columns 7–10 show the ratio of the true fraction of false positives in the likelihood-ratio test to the fraction α expected under the assumption that the LRS is distributed as χ2 with 1 d.f., across a range of α-values. We performed 106 neutral Wright–Fisher simulations with the initial allele frequency ν0 = 0.5. See Table S1 for results for other initial frequencies. Simulations with absorption events were excluded from the analysis.