Table 6  The effect of the transmission bottleneck, N0, and recombination rate, r, on the mean numbers (1000 replicate simulations) of escape epitope fixations at 78 d (E78) and 200 d (E200) p.i
N0rE78E200
10.52.51*8.30*
0.12.408.14
0.012.197.19
0.0012.136.65
02.096.56
100.54.5211.97
03.269.11
  • Other parameter values are cmin = 0.09 and b = 0.18. Asterisks indicate matches to observed numbers of fixed escape epitopes at both time points rounded to the nearest whole number: E78 = 3 and E200 = 8.