Table 1 

Plasma lipids, glucose, and body composition in fourth- and fifth-generation DO mice fed standard chow

FemalesMales
PhenotypeMean ± SEMinMaxMean ± SEMinMax
CHOL (mg/dl)77 ± 343119103 ± 362163
HDL (mg/dl)60 ± 2329778 ± 251124
TG (mg/dl)112 ± 635219167 ± 1064415
GLU (mg/dl)160 ± 474248193 ± 4125279
WT 1 (g)24.2 ± 0.518.536.831.8 ± 0.722.145.2
WT 2 (g)27.8 ± 0.719.142.636.4 ± 0.825.753.4
Change in WT (g)3.5 ± 0.4−211.64.8 ± 0.5−3.313
% Fat 121.8 ± 0.615.131.119.5 ± 0.611.729.3
% Fat 224.0 ± 0.81437.720.9 ± 0.813.331.8
Change in % Fat2.1 ± 0.5−4.69.81.2 ± 0.7−7.910.3
  • Values shown are means ± SE. Min, minimum value within a group for trait measured; Max, maximum value within a group for trait measured. CHOL, total plasma cholesterol; HDL, high-density lipoprotein cholesterol; TG, triglycerides; GLU, glucose. CHOL, HDL, TG, and GLU were obtained after food was removed from mice for 4 hr in the morning. WT 1, % Fat 1, body weight and % body fat at age 12 weeks; WT 2, % Fat 2, body weight and % fat at age 21 weeks. % Fat was obtained by dual-energy X-ray absorptiometry. Changes in weight and % fat were derived by subtracting value 1 from value 2 and are expressed as grams (g) and %, respectively. n = 50 females and 50 males for all measurements except WT 2, % Fat 2, change in WT and change in %Fat, for which n = 48 females and 44 males.