Table 3 Salient features of EGO Complex components
ProteinSizeMotifs/domainsPotential function
Gtr1310 aaRas-family GTPaseGTP-bound form activates TORC1
Gtr2341 aaRas-family GTPaseGDP-bound form activates TORC1
Ego1/Meh1/ Gse2184 aaN-terminal palmitoylation/myristolationaVacuolar recruitment
Ego3/Slm4/Nir1/Gse1162 aaTransmembrane domain, PtdIns(3,5)P2 bindingaVacuolar recruitment
  • a Described in Dubouloz et al. (2005), Hou et al. (2005), and references therein.