TABLE 1

QTL on chromosome 8 for activity on day 2 (saline) using F2, AIL, and integrated analysis

PopulationLOD% variance2-LOD support (cM)2-LOD support (Mb)
F28.1610.1218.7638.80
AIL12.595.370.330.50
Integrated18.907.290.650.50
  • A significant QTL was identified on chromosome 8 using F2, AIL, and the integrated analysis of both populations. The SM/J allele was associated with greater locomotor activity; heterozygotes were intermediate but somewhat more similar to LG/J homozygotes. The 2-LOD support intervals are based on interval mapping. The support interval was smaller in the AIL than in the integrated analysis when expressed in centimorgans but not when expressed in megabases because we did not attempt to interpolate the physical positions of untyped (scanning) loci.