TABLE 3

mett-10 inhibits proliferative fate in the C. elegans germline

GenotypeaTemperatureb% tumorouscn
glp-1(oz264)201100
mett-10(ok2204)15054
mett-10(ok2204)20068
mett-10(oz36)1572107
mett-10(oz36)204166
glp-1(oz264) mett-10(oz36)2010072
mett-10(oj32)15072
mett-10(oj32)20048
glp-1(oz264) mett-10(oj32)204996
mett-10(tm2697)15068
mett-10(tm2697)20076
glp-1(oz264) mett-10(tm2697)2084112
mett-10(g38)15078
mett-10(g38)20056
glp-1(oz264) mett-10(g38)208947
ozIs7[mett-10∷gfp];glp-1(oz264) mett-10(g38)20056
  • a All animals were m+ z−; i.e., they came from mothers carrying a wild-type copy of mett-10.

  • b Animals grown at 15° were scored at 3 days past L4 and animals grown at 20° were scored at 2 days past L4.

  • c Tumorous includes late onset and proliferation throughout the germ line, although some germ cells in various meiotic stages may be observed. Phenotype scored by DIC.