TABLE 1

The mett-10(oz36) tumorous phenotype is the result of a poisonous product

GenotypeaTemperatureb% tumorouscn
mett-10(oz36)1572107
mett-10(oz36)204166
mett-10(oz36)/+15064
mett-10(oz36)/+20070
ozIs7[mett-10∷GFP]; oz3615076
ozIs7[mett-10∷GFP]; oz3620080
mett-10(oz36)/mett-10(ok2204)15032
mett-10(oz36)/nDf4015044
smg-2(e2008); mett-10(oz36)/+20054
smg-2(e2008); mett-10(oz36)/mett-10(g38)201840
smg-2(e2008); mett-10(oz36)209880
smg-2(e2008); glp-1 (bn18) mett-10(oz36)150128
smg-2(e2008); glp-1 (bn18) mett-10(oz36)20098
  • a Full genotypes of the mutant combinations are unc-32(e189) mett-10(oz36)/nDf40 dpy-18(e364), unc-32(e189) mett-10 (oz36)/mett-10(ok2204) dpy-18(e364), smg-2(e2008); unc-36(e251) mett-10(oz36)/unc-119 (ed3), smg-2(e2008); unc-36(e251) mett-10(oz36)/unc-32(e189) mett-10(g38). All animals were m+z-; i.e., homozygous mutants (z-) from mothers carrying a wild-type copy of mett-10.

  • b Animals grown at 15° were scored at 3 days past L4 and animals grown at 20° were scored at 2 days past L4.

  • c Tumorous includes late onset and proliferation throughout the germ line, although some germ cells in various meiotic stages may be observed. Phenotype scored by DIC.